Toronto released its lineup without Guerrero ahead of first pitch, with Addison Barger sliding up to the two hole and Ernie Clement set to handle duties at first base.
There was no indication if Guerrero’s absence was just for a scheduled day off.
The 26-year-old first baseman is slashing .275/.380/.421 with eight home runs and 29 RBIs while appearing in each of Toronto’s 66 games this season.
During Monday’s series-opening win over the Cardinals, Guerrero went 2-for-5 with a double.
With Barger sliding up in the lineup Tuesday, Alejandro Kirk will bat third after his four-hit performance and George Springer will follow in the cleanup spot.
You can watch as the Blue Jays go for a series win behind Chris Bassitt in St. Louis on Sportsnet or stream on Sportsnet+. First pitch is scheduled for 7:45 p.m. ET / 4:45 p.m. PT.
